临床数据表明，对于cdk4/6i治疗失败后的晚期HR+/HER2-乳腺癌患者，羟氯喹联合大剂量cdk4/6抑制剂哌柏西利（200 mg，每天一次）的 ...

Gene expression testing helps determine chemotherapy needs for hormone receptor-positive breast cancer, optimizing treatment ...

Using an unbiased approach, this important study discovered a role of Ezh2 in the differentiation of granule neuron precursors, the cell of origin for Shh group of medulloblastoma. Furthermore, the ...

However, up to half of patients will acquire mutations in the ESR1 gene that can render conventional ... year of treatment with hormone therapy and CDK4/6 inhibitor, a drug that targets certain ...