Background: Establishing a confident clinical diagnosis before an advanced stage of illness can be difficult in Creutzfeldt-Jakob disease (CJD) but unlike common causes of dementia, prion diseases ...

The discovery of ‘new variant’ Creutzfeldt-Jakob disease (vCJD) was announced in March 1996. By mid-1997, several lines of evidence linked vCJD with bovine spongiform encephalopathy (BSE), the ...

An effective blood test for these lethal brain diseases could allow for early diagnosis as well as for curbing their transmission. Prion diseases—including variant Creutzfeldt-Jakob disease ...