Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years have yielded important new insights into ...

Expanding CRISPR's Potential Since its discovery, CRISPR (“Clustered Regularly Interspaced Short Palindromic Repeats”), which ...

Cas12a tool to enable simultaneous genetic modifications, allowing the study of complex genetic interactions in immune system ...

Genetic engineering has revolutionized biomedical research, but optimizing these gene-editing tools remains a challenge. Scientists have now developed a novel approach using an enhanced version of ...

Their CRISPR-Cascade reaction utilizes two ribonucleoprotein complexes, T1 and T2, to achieve amplification-free detection of pathogenic DNA. Upon target recognition, Cas12a in the T1 complex ...

Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years have yielded important new insights into the roles that specific genes play in many diseases. But to date this ...

The new tool, which is called CRISPR-Cas12a, can help researchers simultaneously assess the impact of multiple genetic changes involved in variety of immune system responses, the researchers say.