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优化 HDAC 抑制剂:提升体内外 HDR 相关 CRISPR-Cas9 基因编辑效率
为提升 HDR 相关基因编辑效率,研究人员筛选化合物,发现 HDAC 抑制剂有效,为基因编辑提供新策略。 基因编辑技术近年来在生命科学领域掀起了一阵 “变革之风”,其中 CRISPR-Cas9 系统凭借其独特优势备受瞩目。CRISPR-Cas9(成簇规律间隔短回文重复序列 / CRISPR ...
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