Conversely, stromal cell-derived chemokines such as CXCL13 govern the positioning of T and B cells, establishing SLO structures with segregated zones enriched with different immune cells.

A panel of biomarkers including IFN alpha-2, IFN gamma, CXCL10, CXCL13, B-cell activating factor, interleukin (IL) 7, FLT3, CCL19, and tumor necrosis factor receptor II (TNF-RII) was compared ...