β-catenin is a structural component of the cadherin cell adhesion complex, and also functions in the Wnt growth factor signaling pathway.
为探究可溶性 E - 钙粘蛋白(sE-cadherin)在 ALI/ARDS 中的作用,广州医科大学附属第一医院研究人员开展相关研究,发现 sE-cadherin 通过 VEGF/VEGFR2 通路促进肺炎症,为 ALI/ARDS 治疗提供新方向。 急性肺损伤(ALI)及其更严重的急性呼吸窘迫综合征(ARDS),就像潜伏在 ...
The whole P-cadherin/antibody/drug complex is then sent to a structure called the lysosome to be broken down.
Through comparative transcriptome analysis, Professor Kai-Chien Yang's group identified the adherens junction protein N-Cadherin as a key regulator of CM proliferation and renewal. Its expression ...
SOT109 leverages exatecan-based payload to produce potential best-in-class ADC for validated CDH17 target SOT109 expected to enter a first-in-human Phase 1 clinical trial in 2026 SOTIO Biotech, a ...
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