Dopamine’s effects in the brain are mediated by postsynaptic D1 and D2 receptors. Adenosine A1 and A2A receptors are uniquely positioned to counteract the excessive stimulation of dopamine receptors ...

However, there seems to be more to caffeine's dopamine blocking than just counteracting ... and morphine flick a brain switch known as the μ receptor, which could be targeted.

By blocking these receptors, caffeine may promote the release of dopamine, a neurotransmitter critical to movement control. This release of dopamine can help counteract the neurodegenerative ...

As with any disease, vulnerability to addiction differs from person to person. In general, the more environmental and genetic risk factors an individual has, the greater the chance that taking drugs ...