Cartilage calcification is associated with knee osteoarthritis (OA). A study by Mitsuyama et al., however, suggests that calcification is primarily a consequence of aging rather than OA.

Physiological extracellular matrix (ECM) calcification or mineralization is restricted to bones, teeth and the hypertrophic zone of growth plate cartilage. In contrast, pathological ECM ...

This blue skate’s skeleton is made up of the same stuff as your nose and ears – cartilage. However, parts of a skate’s skeleton, such as the skull and spine, are strengthened by minerals, resulting in ...