Mitochondria in intact cells can transiently accumulate calcium during cell stimulation. The heterogeneity of the response, the extremely high calcium concentrations reached in the mitochondrial ...

Mitochondria are crucial organelles for cellular homeostasis, regulating processes such as ATP production, reactive oxygen ...

Mitochondria are critical for cellular homeostasis, regulating bioenergetics, redox balance, Ca2+ signaling, and cell death.

There are multiple sources for these Ca 2+ increases, including IP3 receptor–mediated Ca 2+ release from the endoplasmic reticulum, release from mitochondria, and influx across the plasma through ion ...

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