Several tumour-suppressor proteins monitor intrinsic and extrinsic signals and integrate these inputs to decide whether the cell should remain in a quiescent state or enter into the cycle of ...

Malignant testicular germ cell tumors are the most common cancers diagnosed in males ages 15 to 39 in the U.S., though incidence has increased by almost 40% in the last 50 years. At the same time, ...

Scheele and her team explored whether the estrous cycle influenced breast tumor cell behavior, potentially explaining the inconsistent results they had observed. By tracking fluorescently-labeled ...

Australian researchers have identified a surprising mechanism focusing on telomeres -- protective caps at the ends of chromosomes -- that can help cells defend against cancer.

This is linked to the cell-cycle-checkpoint functions of the complex, as well as its role in maintaining chromosome stability. Second, we have shown that the Mre11 complex is situated at human ...

Professor Jane Visvader and Associate Professor Shom Goel are recipients of the 2025 Academy honorific awards for their work on advancing breast ...

cancer can emerge. "This work addresses a long-standing mystery surrounding an enzyme critical for regulating the cell cycle and cell proliferation," said senior author Dylan Taatjes, a professor ...

the researchers successfully restored CD8 + T cell activity and slowed tumor growth in preclinical models. Based on these ...

Moreover, the researchers analyzed the effects of miR-377 on apoptosis, proliferation, cell cycle, and wound healing ... in prostate cancer cell lines upon MYC suppression. Additionally, elevated ...