为探究 CARM1 在有丝分裂中的作用,研究人员以其为对象,发现 CDK1 磷酸化 CARM1 S217 促进有丝分裂,拓展了对细胞周期调控的认知。 有丝分裂的神秘 “密码”:CARM1 与 CDK1 的奇妙 “对话” 在细胞的微观世界里,有丝分裂就像一场精心编排的 “舞蹈”,每一个 ...
The genes VEGFA, BRCA1, RAD51, CCNB1, CHEK1, CDK1, and XRCC4 were curated from ... a protein-protein interaction network, accompanied by Gene Ontology and pathway enrichment analysis.
1 They first triggered premature mitotic exit in Xenopus and human cells using inhibitors of cyclin-dependent kinase 1 (Cdk1). This normally also degrades the Cdk1 activator cyclin B. If the ...