0545) has elucidated the molecular mechanisms by which protein phosphatase 2A (PP2A) regulates CD8+ T cell-mediated immune responses. The research, titled "Protein Phosphatase 2A Promotes CD8+ T ...
Trajkovic et al. now report that exosome biogenesis requires the sphingolipid ceramide, whereas the ESCRT (endosomal sorting complex required for transport) machinery is only needed for ILVs that ...