Existing treatments for endometriosis have changed little in the past 30 years and are often ineffective or have undesired ...
A migraine attack is more than a headache. It can derail your entire day.
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Discover the latest breakthroughs in migraine treatment for 2025, including CGRP inhibitors, AI-powered personalized plans, ...
"Plasma Calcitonin Gene-Related Peptide (CGRP) is one of the main neuropeptides involved in migraine pathophysiology and the levels return to normal once the headache subsides. The other chemicals ...
The newest medication class, gepants (CGRP receptor antagonists), targets the specific neuropeptide heavily implicated in migraine pathophysiology. Unlike triptans, these medications lack ...
Pfizer’s Vydura has become the first oral CGRP antagonist recommended for routine use by the NHS to prevent episodic migraine attacks, after being rejected earlier this year as an acute treatment.
It works by blocking a certain protein in the brain and nervous system that can cause migraine. CGRP may cause inflammation and pain in the nervous system of people who have migraine episodes.
AbbVie sells another oral CGRP called Ubrelvy (ubrogepant) for acute treatment of migraine, which made around $552 million last year, and hasn't yet disclosed Qulipta's quarterly sales performance.
This aligns with previous findings that inflammation in TG neurons can contribute to pain spreading to nearby areas, including those related to migraines. A key focus of the study was the potential ...
The American College of Physicians strongly recommends adding a triptan to an NSAID to treat adults with moderate to severe ...