The administration of chemotherapeutic drugs at maximum tolerated doses (MTDs) often induces dose-limiting toxicity in rapidly dividing tissues (intestines, bone marrow, and skin), and so patients ...

One particular challenge in the treatment of cancer is therapy resistance. An international research team has now discovered a mechanism that opens up new treatment strategies for tumors in which ...

Chronic chemotherapy-induced peripheral neuropathy is a substantial burden among people with cancer treated with chemotherapy ...

This pioneering study, published in Nature Structural & Molecular Biology, sheds light on the complex interplay between taxanes—widely used chemotherapeutic drugs—and microtubule acetylation ...

Significant contributions have been made by technological improvements in radiotherapy, as well as by the introduction of novel chemotherapy agents and dosing schedules. This article will review ...