Chimeric Antigen Receptor (CAR) T-cells for immunotherapy of cancer are being developed. These CAR T-cells overcome several limitations of current strategies including the ability to tune CAR T-cell ...
CD19-directed chimeric antigen receptor (CAR) T cells are clinically effective in a limited set of leukemia patients. However, CAR T-cell therapy thus far has been largely restricted to targeting ...
Chimeric antigen receptor-T (CAR-T) cell therapy, initially successful in hematologic malignancies, presents a promising avenue for treating solid tumors, including CRC. This review explores the ...