Background: In addition to the development of stoichiometric reagents, we are interested in the development of selective catalysts for organic synthesis. Our work has focused on two areas, the design ...

Chirality is a fundamental property of asymmetry in nature, where an object or molecule cannot be superimposed onto its mirror image. In the context of nanotechnology, chirality refers to the ...

Chiral 1,2-diamines are common structural motifs in natural products, bioactive molecules, pharmaceuticals, chiral ligands, auxiliaries, and organocatalysts. Given their vital importance, great ...

For the development of asymmetric reductive coupling of imines to form chiral vicinal diamines through the discovery of diboron-enabled [3,3]-sigmatropic rearrangements. The team has developed a new ...

Scripps Research chemists have accomplished a long-elusive feat in synthetic chemistry: the invention of a broadly useful method for constructing "gamma chiral centers" on simple starting ...