Histone modifications alter the structure of chromatin, affecting how tightly the DNA is packaged and influence gene expression. Similarly, transcription factors, which bind to the DNA, are essential ...

We study all of the protein components of chromatin with an emphasis on understanding how multiple sources of variation function in concert or combination with each other. A major, but not exclusive ...

Citrullination, a transformative protein post-translational modification, is gaining recognition for its wide-ranging impact ...

Citrullination, a transformative protein post-translational modification, is gaining recognition for its wide-ranging impact on cellular function and human disease.

Dr. Antonio Bedalov studies chromatin, the material that makes up the chromosomes of humans and other eukaryotes. He is learning how chromatin modifications influence important biological events ...

EDINBURGH, Scotland, April 14, 2025 /PRNewswire/ -- Chromatin Bioscience, a leader in the design of synthetic promoters and gene control systems, is pleased to announce a collaboration agreement ...

Epigenetic changes, including histone modifications and proteome, are critical regulatory mechanisms, involved in all developmental processes including aging and age-associated diseases. The goal of ...

ERIL provides MSK researchers with state-of-the-art epigenetics research resources and services to study cancer-associated changes in chromatin accessibility, DNA methylation, and histone ...