Here, we focus on how chromatin modifications and structure are propagated; we first summarize how replication occurs and then consider models of histone segregation. Importantly, the initiation ...

It will then focus on the function of menin in linking transcriptional pathways to chromatin modification, and discuss the putative implications of recent findings for the clinical manifestations ...

The research could contribute to the development of more effective anti-aging treatments in the future. The body's aging ...

A novel, freely available AI tool has cut the time it takes to determine chromatin structure from days to minutes. The 3D ...

Use precise geolocation data and actively scan device characteristics for identification. This is done to store and access ...

The way the body ages could be more resilient than previously thought, a new study suggests.

These modifications increase chromatin accessibility, influencing growth, differentiation, and ion transport, with contrasting effects on normal and colorectal cancer cells. Study: Short-chain ...

New AI model takes minutes rather than days to predict how a specific DNA sequence will arrange itself in the cell nucleus.

Epigenetic modifiers, enzymes that catalyze covalent modifications on chromatin, play a pivotal role in establishing stable states for gene expression and cellular identity. Mutations in these ...

Short-chain fatty acids (SCFAs) like propionate and butyrate are critical byproducts of dietary fiber digestion. These molecules do more than fuel the body—they directly influence gene expression and ...

Chromatin, the mix of DNA and protein that houses each cell's genome, is more resilient to aging than previously thought, suggests a study published in the Journal of the American Chemical Society by ...

The way the body ages could be more resilient than previously thought, a new study suggests.