The chromatin landscape is a key aspect of epigenetic ... duplicates the histone marks between the corresponding tails of a nucleosome if the segregation occurs as dimers, or between adjacent ...
Starting with the structure of the nucleosome and continuing with histone modifications, chromatin-remodeling complexes, silencing factors and more, a detailed and dynamic picture of chromosomal ...
A cable drum (consisting of four pairs of histones) with coiled DNA is called a nucleosome and is the smallest unit of chromatin. Known as the supportive scaffold for chromatin, the nuclear matrix ...
Inspired by the UV light-based immunochemical approach developed by Lis and Gilmour, the team decided to use antibodies to capture a histone of interest, in this case histone 4 (H4), one of the ...
Chromatin is the physiological state of the genome. Approximately 50% of chromosomes and chromatin is protein. These include histones, transcription factors, nuclear receptors, co-activators, ...
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Study reveals how transcription factors navigate DNA architecture to shape cellular identityA significant discovery was the role of chromatin topology—the folding ... The research, titled "Nucleosome fibre topology guides transcription factor binding to enhancers," is published in ...
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