Despite this shortening, a half-foot of chromatin is still much too long to fit into the nucleus, which is typically only 10 to 20 microns in diameter. Therefore, chromatin is further coiled into ...

A novel, freely available AI tool has cut the time it takes to determine chromatin structure from days to minutes. The 3D ...

Murre and his colleagues hypothesized that proteins controlling the folding and packaging of DNA in the nucleus might also influence the overall architecture ... further investigations into the ...

A generative AI-based technique can predict thousands of 3D genomic structures in just minutes, enabling researchers to more ...

ChromoGen: A quick method to determine 3D genomic structures using generative AI, enabling the prediction of thousands of ...

Inside the cell nucleus, DNA and proteins ... and how those differences affect their function. The model could also be used to explore different chromatin states that can exist within a single ...

these packages are called chromatin. Mistakes of that kind can lead to a host of problems. It turns out that TET2 regulates ...

In the nucleus, actin has been linked to many processes that regulate gene expression, such as transcription factor regulation, RNA polymerase function and chromatin remodeling, as well as to DNA ...