The epigenetic state of chromatin, gene activity, and chromosomal positions are interrelated. A research team from the IPK Leibniz Institute (IPK) and the Karlsruhe Institute of Technology (KIT) ...
Understanding these rearrangements is crucial for studying chromosomal evolution, as they can provide insights into how species adapt and evolve over time. Recent research has focused on ...
In addition, the detailed analysis of these rearrangements is expected to ... Before hybridization, metaphase chromosomes on slides were treated with 100 μg/ml RNase for 1 h at 37 °C and 30 ...
For the first time in humans, researchers have discovered a large chromosomal rearrangement that bears the mark of natural selection, they report in the February issue of Nature Genetics. The ...
By confirming that the Denisovans and Neanderthals both share these same chromosomal rearrangements, the study authors conclude that this vital speciation event occurred before Homo sapiens split ...
Chromosome imbalance caused by the absence or duplication of chromosomal material most often results in spontaneous abortion. In a live birth, chromosomal imbalance generally produces some ...
This event is thought to coincide with significant chromosomal rearrangements, including the fusion of chromosome 2 and the translocation of the pseudoautosomal region 2 (PAR2) from chromosome X to Y.
Our group has pioneered the use the CRISPR-Cas9 technology to engineer chromosomal rearrangements in vivo. In 2014 we described a simple strategy to engineer an oncogenic chromosomal inversion leading ...