During meiosis, sister chromatids produced by chromosome duplication are held ... manner that correlates with the loss of sister-chromatid cohesion. Figure 1: Regulation of sister-chromatid ...

A key target of the APC is securin, the destruction of which initiates chromosome segregation by unleashing the protease separase, which destroys sister-chromatid cohesion. The APC also ...

The wide variety of congenital anomalies often accompanying constitutional aplastic anemia has led to its recognition as a distinctive syndrome. Congenital malformations have been the outstanding ...

Each replicated chromosome is made up of two identical strands called chromatids that are joined together. Each chromatid is a full length DNA molecule. The stages outlined in the following ...

Chromatid aberrations in peripheral leukocytes ... Moreover, although it is not known in what stage the chromosomes of reticuloendothelial-tissue stem cells or precursors of peripheral leukocytes ...

Each chromosome is, at this time, actually two identical copies. Each copy is called a chromatid. A spindle begins to form from the centrioles. This spindle is made of fibers. The centrioles begin ...