Through single-cell RNA-sequence analysis comparing young mice (8–10 weeks old) with aged mice (18–20 months old), the researchers identified Clusterin (Clu), a molecular chaperone ...

Expression of the clusterin gene in hematopoietic stem cells marks an age-related shift toward myeloid/platelet over lymphoid cell production In recent years, there has been a growing trend of an ...

Mass General Brigham researchers have identified a potential strategy to protect against Alzheimer's disease by increasing the clusterin protein (CLU). Their results, published in Neuron ...

Through single-cell RNA-sequence analysis comparing young mice (8–10 weeks old) with aged mice (18–20 months old), the researchers identified Clusterin (Clu), a molecular chaperone ...

In a new study published in Neuron titled “CLU alleviates Alzheimer’s disease-relevant processes by modulating astrocyte reactivity and microglia-dependent synaptic density,” researchers ...