A less-virulent poliovirus generated by altering codon usage suggests a new strategy for vaccine development. Figure 1: Development of an attenuated vaccine by two classical methods and the ...

Following this discovery, Nirenberg, Philip Leder, and Gobind Khorana identified the rest of the genetic code and fully described each three-letter codon and its corresponding amino acid.

This advancement, published in Nature, describes the creation of a genomically recoded organism (GRO) named 'Ochre'. It uses a single stop codon, enabling the production of synthetic proteins with ...

It uses a single stop codon, enabling the production of synthetic proteins with innovative properties ... This research builds on previous work published in Science in 2013. It represents a ...

Kamal is a freelance science journalist based in the UK with a PhD in virology from the University ... they found that the TCG triplet introduced the new building block into the protein at the highest ...

More information: Md Noor Akhtar et al, Hominini-specific regulation of the cell cycle by stop codon readthrough of FEM1B, Journal of Cell Science (2024). DOI: 10.1242/jcs.261921 ...