The modification state helps determine whether the nucleosome is an appropriate substrate for a remodeler complex (Saha et al., 2006), as discussed later in this article. Chromatin structure is ...

A nucleosome is a section of DNA that is wrapped around a core of proteins. Inside the nucleus, DNA forms a complex with proteins called chromatin, which allows the DNA to be condensed into a ...

A significant discovery was the role of chromatin topology—the folding ... The research, titled "Nucleosome fibre topology guides transcription factor binding to enhancers," is published in ...

A cable drum (consisting of four pairs of histones) with coiled DNA is called a nucleosome and is the smallest unit of chromatin. Known as the supportive scaffold for chromatin, the nuclear matrix ...

Approximately 50% of chromosomes and chromatin is protein. These include histones, transcription factors, nuclear receptors, co-activators, co-repressors, histone modifying enzymes, nucleosome binding ...

Nucleosome positions and histone modifications are critical ... the process of DNA replication intrinsically disrupts nucleosomes ahead of the fork raising the question how chromatin structure is ...