MSK researchers shed new light on G-quadruplexes, a type of secondary DNA structure that has attracted attention as a potential therapeutic target in cancer.

Using cryo-electron microscopy (cryo-EM), a team of structural and molecular biologists at Memorial Sloan Kettering Cancer Center (MSK) set out to investigate G4s -- which have gained attention as ...

This study reveals how SV40 helicase unwinds DNA, highlighting ATP hydrolysis's role in translocation and offering insights ...