By freezing the sample and observing in a cryogenic-SEM and cryo-TEM, the nano-scale features are observable as if the sample is a conductive solid, and thin sections on a 100nm scale are possible.

We used lipid nanoparticles to deliver mRNA and siRNA to human PCa cells to evaluate our technique’s ability to both restore the lost PTEN and silence the overexpressed AR. Our strategy could ...

2023 is set to be a landmark year for lipid-based delivery technology development and the 2nd Next-Generation Lipid-Based Nanoparticle Delivery Summit returns to unite 140+ biopharma thought ...

We used lipid nanoparticles to deliver mRNA and siRNA to human PCa cells to evaluate our technique's ability to both restore the lost PTEN and silence the overexpressed AR. Our strategy could also ...

A new framework bridges a gap in understanding RNA therapeutics by linking the structure of lipid nanoparticles to immune ...

Using cryo-electron microscopy, the scientists observed that the lipid organization of these microdomains is altered in response to mechanical stimuli. "We discovered that when the eisosome ...