A new study in Nature identifies a long-sought cytoplasmic 'sensor' that is responsible, at least in part, for interferon responses induced by double-stranded DNA. How do cells detect non-self ...

Over the past decade, there have been scattered reports of mammalian cells’ own DNA being found in the cytoplasm, mainly in the context of disease and aging. While it is not unusual to find DNA from ...

DNA is a single molecule, found free in the cytoplasm; additional DNA is found on one or more rings called plasmids. Eukaryotic cell DNA in a nucleus, plasmids are found in a few simple eukaryotic ...

Adenine and guanine are double-ring molecules called purines ... spindly structures called centromeres. However, the DNA exposed to the cytoplasm is exposed to whatever else is circulating ...