A new pill, tavapadon, has shown potential in easing Parkinson’s symptoms while limiting side effects. In patients taking at ...

"Instead, we found the types of dopamine receptors on the brain cells, and the ratio in which they are found, better predicted cognitive performance." Study participants who had a higher ratio of ...

The highly selective partial agonist at D1 and D5 receptors significantly improves motor function in patients recently ...

Theranocure Co. Ltd. has prepared and tested new vanillic acid derivatives targeting the dopamine D1 receptor (D1R) reported to be useful for the treatment of neuroinflammation and Alzheimer’s disease ...

Dopamine’s effects in the brain are mediated by postsynaptic D1 and D2 receptors. Adenosine A1 and A2A receptors are uniquely positioned to counteract the excessive stimulation of dopamine receptors ...

Fixed and flexible doses of tavapadon significantly improved motor function compared with placebo in patients with ...

A new study in Engineering explores the role of astrocytic G protein-coupled receptors in drug addiction. It shows that these receptors, including ...

Here, the authors report a modular click ligand-directed approach to covalently attach fluorescent dyes to endogenous dopamine D1 receptors in live cells. CXCR3 and CXCR7 are chemokine receptors ...

In the study, Tavapadon, which works by mimicking dopamine and targeting the D1/D5 receptors, was found to have the same benefits as levodopa without the adverse effects, according to Hubert H.

Study participants who had a higher ratio of D1-to-D2 brain dopamine receptors performed better on memory tasks during baseline testing compared to those who had a higher ratio of D2 receptors ...