A new pill, tavapadon, has shown potential in easing Parkinson’s symptoms while limiting side effects. In patients taking at ...

Dopamine’s effects in the brain are mediated by postsynaptic D1 and D2 receptors. Adenosine A1 and A2A receptors are uniquely positioned to counteract the excessive stimulation of dopamine receptors ...

Theranocure Co. Ltd. has prepared and tested new vanillic acid derivatives targeting the dopamine D1 receptor (D1R) reported to be useful for the treatment of neuroinflammation and Alzheimer’s disease ...

The highly selective partial agonist at D1 and D5 receptors significantly improves motor function in patients recently ...

A new study in Engineering explores the role of astrocytic G protein-coupled receptors in drug addiction. It shows that these receptors, including ...

"Instead, we found the types of dopamine receptors on the brain cells, and the ratio in which they are found, better predicted cognitive performance." Study participants who had a higher ratio of ...

Our brain cells have different types of chemical receptors that work together to produce optimal performance of brain function. Differences in the balance of these receptors can help explain who is ...

Fixed and flexible doses of tavapadon significantly improved motor function compared with placebo in patients with ...

1995; Yasuda et al. 1988). Instead, both OPC-14597 and OPC-4392 exhibit clear antagonist actions at postsynaptic receptors, as evidenced by inhibition of apomorphine-induced stereotypy and ...