Dopamine’s effects in the brain are mediated by postsynaptic D1 and D2 receptors. Adenosine A1 and A2A receptors are uniquely positioned to counteract the excessive stimulation of dopamine receptors ...

the D1 receptors, which activate neurons, and the D2 receptors, which inhibit them. A third group of dopamine receptors that possess both D1 and D2 dopamine receptors was known to exist ...