DNA is fundamental to the biology of all life on Earth, but how many of us actually know what it is or what it's made of?

Adjacent ribose nucleotide bases are chemically attached to one another in a chain via chemical bonds called phosphodiester bonds. Unlike DNA, RNA is usually single-stranded. Additionally ...

(Remember, DNA is almost always in a double-stranded helical form.) Furthermore, RNA contains ribose sugar molecules, which are slightly different than the deoxyribosemolecules found in DNA.

1 In their 1953 publication on the DNA double helix, Watson and Crick stated: "It is probably impossible to form this structure with ribose, instead of deoxyribose." The reason: The 2' hydroxyl on ...

DNA and RNA use the same five-carbon sugar, ribose, in their structure. The deoxy- means that on one side of the base pair, there's a place where another base pair can attach itself by way of a ...

Later it was found that the sugar in nucleic acid can be ribose or deoxyribose, giving two forms: RNA and DNA. In 1943, American Oswald Avery proved that DNA carries genetic information.

With a composition quite similar to DNA, RNA is able to perform ... Below 5ºC, the new RNA stability is determined by ...

It is a polymeric molecule composed of nucleotides, each containing a ribose sugar, a phosphate group, and one of four nitrogenous bases: adenine (A), uracil (U), guanine (G), or cytosine (C). RNA is ...

In DNA and RNA, purines pair with their complementary pyrimidine bases ... It consists of an adenine base, a ribose sugar, and three phosphate groups. The hydrolysis of ATP releases energy that is ...

PARylation is integral to many key cellular functions, including signaling modulation and DNA repair. PARylation is reversible and is undone by PAR erasers such as poly ADP-ribose glycohydrolase (PARG ...

ATP-dependent RNA ligases join 3’-OH and 5’-PO 4 RNA termini via three nucleotidyl transfer steps similar to those of DNA ligases: (Step 1) ligase reacts with ATP to form a covalent ...