Chromatin remodeling plays a vital role in gene regulation, affecting how DNA is accessed. Disruptions in this process can ...

A team led by Professor Kazuhiro Maeshima of the National Institute of Genetics (ROIS) and SOKENDAI in Japan has developed a ...

In eukaryotes, DNA is tightly wound into a complex called chromatin. Thanks to the process of chromatin remodeling, this complex can be "opened" so that specific genes are expressed. Various ...

so histones bind with DNA very tightly. The basic repeating structural (and functional) unit of chromatin is the nucleosome, which contains eight histone proteins and about 146 base pairs of DNA ...

Kanazawa University and colleagues have achieved a breakthrough in understanding sperm DNA packaging. Using high-speed atomic force microscopy (HS-AFM), they captured the real-time process of ...

New research delves into the DNA details and chromatin structures that may predict prognosis in early-stage lung ...

To fit such a long molecule within the tiny space of the nucleus, DNA bends and loops in several ways. The largest of these loops results from the helical coiling of chromatin (the thick line in ...

To do so, they planned to stabilize proteins at their chromatin binding locations and use nucleic acid hybridization to fish out specific DNA sequences along with the bound proteins. By using enzymes ...

Now, for the first time, EMBL scientists have directly observed this process in high resolution under the microscope using a new chromatin tracing method. The new study shows that the long DNA ...

A novel technique to visualize gene-active and gene-repressive DNA regions in living cells, developed by a ...