They can also be produced when DNA replication forks encounter DNA single-strand breaks or other types of lesion. They can occur at the termini of chromosomes due to defective metabolism of ...

Researchers from Agency for Science, Technology and Research in Singapore recently published a review article exploring how ...

Scientists have provided the most detailed account yet of the earliest stages of DNA replication, an essential process for ...

New precision genome editing technologies are transforming the therapeutic landscape for patients with certain cancers and ...

The double ring, spool-like structure of RAD52 protects replicating DNA in dividing cells. A study led by the University of ...

For DNA to replicate, the helix must first unwind and break the DNA from a double strand into two single strands. Upon binding, helicases melt the DNA, breaking the chemicals bonds holding the ...

In a study published in Nature, researchers report the successful in vitro reconstitution of meiotic DNA double-strand breaks ...

A new study in the journal Human Gene Therapy indicates that DNA impurities derived from plasmid and host cell DNA are ...

DNA helicases are essential during DNA replication because they separate double-stranded DNA into single strands, allowing each strand to be copied. Dr Taha Shahid, from the University of ...