帕金森病（PD）与黑色素瘤的关联机制不明，研究人员开展 α-Synuclein（αSyn）在黑色素瘤中作用的研究。结果显示，αSyn 在黑色素瘤核仁富集，参与 DNA 双链断裂（DSB）修复，影响细胞增殖等。该研究为理解二者关联提供依据，有重要意义。

A new study from Weill Cornell Medicine provides insights into how cells maintain the tiny end caps of chromosomes as they divide, a key process in keeping cells healthy. Using yeast, the researchers ...

A few years ago, the advent of technology known as CRISPR was a major breakthrough in the scientific world. Developed from a ...

Cells use many complex genetic repair backup systems to fix DNA damage and remain healthy throughout their lives.

For the first time, Professor Veyrier and his team at INRS have discovered a family of enzymes that can cut specific sequences in single-stranded DNA. These enzymes, called site-specific ...

Learn about Brink Tx as it raises $4 million to go beyond CRISPR with engineered recombinases in CAR T therapy.

A new study reveals that the protein alpha-synuclein, known for its role in Parkinson’s disease, also contributes to the ...

Study reveals alpha-synuclein's role in enhancing DNA repair in melanoma, linking Parkinson's protein to cancer cell survival ...

Introduction: The DNA of a Biotech BoomThe global plasmid DNA manufacturing market is entering a transformative era, driven ...

Mitochondrial diseases, arising from mutations in mitochondrial DNA (mtDNA), are a diverse group of disorders that lead to ...