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生物通
4 天
GC-DNA 片段调控乳腺癌细胞生存基因表达,TLR9/MyD88/NF-κB 通路成癌症 ...
为探究无细胞 DNA(cfDNA)中富含 GC 的 DNA(GC-DNA)对癌细胞的作用,研究人员开展了 GC-DNA 对野生型 MCF7 细胞(wt MCF7)和 TLR9-/-MCF7 细胞生存基因转录活性影响的研究。结果发现 TLR9-/-MCF7 细胞经 GC-DNA 刺激后相关信号级联活性及生存基因表达下降,该信号级联可作 ...
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