In cells, the DNA helix is often overwound, causing a phenomenon known as supercoiling. In the nucleus, DNA forms a complex with proteins. This complex is called chromatin and is formed when the ...

Researchers harness the power of the world’s most advanced supercomputers to simulate the inner workings of cellular ...

Chances are you've seen an illustration of DNA's double-helix structure and even pictures ... each working together in a complex symphony of interactions. With the exception of red blood cells ...

In their latest study, published in Nature Communications, the team has built a computer model of a critical NER component called the pre-incision complex ... twists the DNA helix to make the ...

The findings visualize for the first time a molecular complex—called CTF18-RFC in ... turning a single DNA helix into two. Much of this work falls to enzymes called polymerases, which assemble ...

For DNA to replicate, the helix must first unwind and break the ... could harness similar energy-efficient mechanisms to perform complex, force-driven tasks," he said.

"The DNA double helix is one of the most recognizable molecular ... to block or enhance the activity of a particular protein ...

DNA is a complex molecule that consists of two strands coiled around each other to form a double helix structure. Comparison of a single-stranded RNA and a double-stranded DNA with their corresponding ...

resulting in adoption of an RNA-like A-form helix, again echoing the findings for the HuLig1-DNA cocrystal. A metal-driven mechanism was revealed by our recent crystal structure of Naegleria gruberi ...