Promoter sequences are DNA sequences that define where transcription of a gene by RNA polymerase begins. Promoter sequences are typically located directly upstream or at the 5' end of the ...

In addition, regulatory sites on prokaryotic DNA are typically located close to transcription promoter sites — and this plays an important part in gene expression. For an example of how this ...

A new study published in PLOS Genetics has identified an extreme mutational hotspot within the genome of Pseudomonas ...

Researchers at the University of Tsukuba have developed a vector that integrates the Cre enzyme gene with the specific DNA ...

There is no discernable significant homology between human and either chicken or zebrafish insulin promoters, which is in keeping with the view that most human DNA is not alignable to species ...

A differentiable variant of the Gillespie algorithm enables gradient-based optimization for stochastic chemical kinetics, facilitating efficient parameter estimation and the design of biochemical ...

Eight promoter-edited alleles of GhCKI were obtained ... editing the promoter region of the key high-temperature-responsive gene GhCKI. This breakthrough provides novel genetic resources and ...

And third, the promoter should be insulated from surrounding DNA by including extra DNA before it to further reduce leakiness. We showed that a promoter's performance can be improved more than 100 ...

While previous research had described bidirectional promoters in eukaryotes ... widespread feature conserved across all three domains of life. In eukaryotic cells, DNA winds around histone ... Jack is ...

The numbers of the principal regulatory elements present in insulin promoters are listed. Given the complexity and uncertainty of predicting the transcriptional outcome of mutations within ...