Promoter sequences are DNA sequences that define where transcription of a gene by RNA polymerase begins. Promoter sequences are typically located directly upstream or at the 5' end of the ...

Researchers at the University of Tsukuba have developed a vector that integrates the Cre enzyme gene with the specific DNA ...

A new method for mapping torsion provides insights into the ways that the genome responds to the torsion generated by RNA polymerase II.

A new study published in PLOS Genetics has identified an extreme mutational hotspot within the genome of Pseudomonas ...

There is no discernable significant homology between human and either chicken or zebrafish insulin promoters, which is in keeping with the view that most human DNA is not alignable to species ...

Eight promoter-edited alleles of GhCKI were obtained ... editing the promoter region of the key high-temperature-responsive gene GhCKI. This breakthrough provides novel genetic resources and ...

And third, the promoter should be insulated from surrounding DNA by including extra DNA before it to further reduce leakiness. We showed that a promoter's performance can be improved more than 100 ...

The numbers of the principal regulatory elements present in insulin promoters are listed. Given the complexity and uncertainty of predicting the transcriptional outcome of mutations within ...

While previous research had described bidirectional promoters in eukaryotes, as well as in a few bacteria and archaea species, the new study establishes divergent transcription—the reading of genes in ...