a unique technology able to produce antibodies that not only target and penetrate cancer cells, but bind to their DNA and block their repair enzymes, halting further progression. Antibodies have ...

Homologous recombination plays essential roles in the repair of DNA double strand breaks (DSBs) and collapsed replication forks. The fundamental reaction in homologous recombination is the exchange of ...

The genetic connections between DNA repair pathways and human cancer predisposition have fueled interest in the proteins that recognize and repair specific sites of DNA damage. The repair enzymes are ...

This protein is an enzyme that helps repair a specific type of DNA damage —- namely ... cells that help them to work properly ...

Researchers from the University of Birmingham have uncovered answers that provide the detail to explain two specific DNA repair processes that have long been in question. The publication of two ...

“We thought maybe this is a method to shed some light on the mode of action of these [monoclonal] antibodies,” said Sauer. Sauer and his team started out by improving on a technique called DNA-based ...

A research team has unveiled a crucial mechanism that helps regulate DNA damage repair, with important implications for improving cancer treatment outcomes. The result was published in Cell Death ...

In this Review, familial and sporadic neurological disorders reported to have an etiological link with DNA repair defects are discussed, with special emphasis placed on the molecular link between ...

Additionally, in the framework of a licensing agreement and a collaborative endeavor to support innovative research, Debiopharm and Oncodesign Services will present promising new data illustrating how ...