At different times during the life cycle of a cell, the DNA that makes up the cell's chromosomes can be tightly compacted into a structure that is visible under a microscope, or it can be more ...

How is all of that DNA packaged so tightly into chromosomes and squeezed into ... may be highly irregular and not quite the uniform structure depicted in instructive drawings such as Figure ...

The nucleus of each human body cell contains 46 chromosomes. Each chromosome contains about 1000 genes. There is enough DNA in all the cells in a human body to stretch to the sun and back again ...

Rethinking Models of DNA Organization in Micrometer‐Sized Chromosomes from the Perspective of the Nanoproperties of Chromatin ...

Scientists worked out the structure of DNA in the 1950s ... This is why children resemble both their parents – half of their chromosomes and DNA come from their mother, and half from their ...

Chances are you've seen an illustration of DNA's double-helix structure and even pictures of the chromosomes that comprise the human genome. But where and how does the famous double helix fit into ...

Management of chromosome shape and topology in bacteria falls to three groups of proteins: the DNA topoisomerases, the structural maintenance of chromosome proteins (SMC), and the small double-strand ...

Two new studies show how a seeming tangle of DNA is actually organized into a structure that coordinates thousands of genes ...

This valuable work extends previous studies to convincingly show that the centromere-histone core contributes to force transduction through the kinetochore. The centromere mainly strengthens one of ...

Torsional stress in chromatin plays a fundamental role in cellular functions, influencing key processes such as transcription, replication, and chromatin organization. Transcription and other ...

These findings help us better understand the structure and function of our chromosomes. They also provide insight into how disruption of twisted DNA looping can affect health—for instance ...

So, it's very easy to see,” she said. To zoom in on changes in chromosome organization during meiosis, the researchers used nuclear membrane and DNA damage protein stains to track nuclear behavior.