Gain expert insights in this interview on achieving transfection success. Explore proven strategies to optimize your approach and enhance results.

Transcription initiation sites are locations in the DNA where a specialized transcription-factor protein can attach and then build an mRNA copy of the gene in front of it. That mRNA is read and ...

The yeast RGG motif-containing RNA binding protein Scd6 and its human ortholog LSM14A regulate the translation of specific ...

Bin Wu, associate professor in the department of Biophysics and Biophysical Chemistry at the School of Medicine, visited ...

causing changes in gene expression without changing the DNA sequence itself. Thus, vaccination with mRNA vaccines could lead to an enhanced immune response to future encounters with pathogens ...

One researchers explained that bacteria do a really, really good job of keeping the sequence you want and the sequence that you get.

Providing the breakthrough The two mRNA vaccines ... or transcription activator-like effector nucleases (TALEN). This could enable a type of therapy that would precisely alter the DNA to ...

The new approach builds directly on the genetic medicine revolution that began at Penn: the development of safe messenger RNA (mRNA) therapies used in COVID vaccines. "For 20 years, DNA delivery ...

Researchers from Agency for Science, Technology and Research in Singapore recently published a review article exploring how chromatography can be used to remove double-stranded RNA impurities during ...

IMUNON chose a DNA-based approach for COVID-19 because it builds on our expertise in DNA therapeutics and offers distinct advantages over mRNA and traditional vaccines. We saw an opportunity to create ...

They exist as circular pieces of DNA in the nuclei of tumor cells outside chromosomes. Transcription of the amplified ecDNA genes can promote oncogenic processes, such as the increased expression ...