The clinical utility of the cancer chemotherapeutic agent doxorubicin (DOX ... preferentially accumulates in heart during chronic DOX administration. We now find that DOXol is cardioactive ...

It says that when mice were given high doses of doxorubicin chemotherapy and the activity of this enzyme was blocked, it was found that the rodents were protected against heart failure.

Doxorubicin HCl 10mg/vial ... (including left ventricular failure), arrhythmias. Pre-existing heart disease or risk thereof. Obtain CBCs, bilirubin, SGOT/SGPT, creatinine, LVEF prior to and ...