In this study, Sander et al. 1 measured the responsiveness of blood flow in normal and DMD muscle during exercise, and observed that dystrophin loss impairs regulation of the vasoconstrictor response.

Earlier, DYN reported mixed data from its ongoing phase I/II study, the DELIVER trial of DYNE-251 in patients with Duchenne ...

Without functional dystrophin to support muscle strength and stability, muscle fibers are easily damaged. Duchenne muscular dystrophy results from mutations in the DMD gene that encodes the dystrophin ...

a study that included 16 DMD patients, with 8 patients receiving Viltepso at the recommended dose. In the study, dystrophin levels increased, on average, from 0.6% of normal at baseline to 5.9% of ...

Some types of muscular dystrophy typically affect only males; some people with MD enjoy a normal life span ... with this gene was named dystrophin. Duchenne muscular dystrophy occurs when that ...

Duchenne muscular dystrophy (DMD) is a rare genetic disorder that is characterised by progressive muscle degeneration and weakness, and is caused by mutations in the dystrophin gene. Currently ...