One of the major constituents of the cell-adhesion complex in epithelial cells is E-cadherin, a transmembrane protein involved in homotypic cell–cell adhesion. E-cadherin exerts a potent ...

This leads to EMT, as evidenced by a decrease in E-cadherin expression. (Bottom) Fluorescence signal showing the decrease in E-cadherin (left) and increase in alpha-SMA (right) in kidney cells ...

The cells didn't bind to another type of the cadherin protein—epithelial, or E-cadherin—also typically found within the subventricular zone. The scientists noticed that the neural stem cells ...

As a conclusion, this work not only identifies mTOR and E-cadherin as key components in maintaining dormancy but also offers a promising roadmap for future therapies. By targeting these pathways ...