They offer innovative diagnostic and therapeutic options. As an example, modulation of TGF-β/BMP-7 ratio changes the rate of EMT, and so the simultaneous determination of these parameters and of ...

Lipid metabolism has emerged as a central player in the progression and therapy resistance of breast cancer, particularly the aggressive subtype known as triple-negative breast cancer (TNBC).

Among these factors, the transforming growth factor (TGF)-β family is ... a process named epithelial–mesenchymal transition or transformation (EMT), and in this way they contribute to the ...

Below: A “hot” tumor, which has been infiltrated by lymphocytes (red), and is already considered vulnerable to checkpoint inhibitor therapy. Normally, TGF-Beta soothes the immune system, and some ...