The protein folding machinery of the endoplasmic reticulum is coupled to the burden ... have pointed out that the groove in the crystal structure of the lumenal domain of the related human protein ...

A protein's function directly depends on its folded structure. Additionally ... sarcoplasmic reticulum — a specialized type of endoplasmic reticulum found in muscle cells.

dynamic network of tubules that plays an important role in protein transport and quality control, cellular signaling, and stress response. Investigating how the unique structure of the ER arises ...

Oregon Health & Science University, in collaboration with Oregon State University, has discovered the structural organization ...

Our research focus is currently on ER receptor complexes and adhesion protein interactions, and broadly on the structural biology of proteins, with a variety of biophysical, biochemical, and cell ...