investigated the potential of the histamine H1 blocker hydroxyzine to improve sleep in patients with cirrhosis and minimal hepatic encephalopathy. All 35 patients (mean age 56 years [range 36–69 ...

"In the absence of strong supportive evidence from future trials, use of hypothermia is not indicated in infants born with hypoxic-ischemic encephalopathy ... occurred at a mean of 4.5 hours.