The endoplasmic reticulum (ER) is a compartment (organelle) in eukaryotic cells that consists of membrane sacs called cisternae. Because of the bound ribosomes, the 'rough' ER is the site of ...

focusing on its role in pathogenesis through alterations in the endoplasmic reticulum (ER). In addition to engulfing superfluous cellular material, macrophages also handle hazardous lipid cargo in ...

The endoplasmic reticulum (ER) is a crucial organelle present in all eukaryotic cells, including human cells. The ER plays a ...

The peripheral endoplasmic reticulum (ER) forms a continuous, dynamic network of tubules that plays an important role in protein transport and quality control, cellular signaling, and stress response.

In biology textbooks, the endoplasmic reticulum is often portrayed as a distinct, compact organelle near the nucleus, and is ...

Er Stress Research Institute Inc. has disclosed benzothiazoimidazolyl compounds acting as endoplasmic reticulum (ER) stress inhibitors reported to be useful for the treatment of cancer, diabetes, ...

New research, published recently in Proceedings of the National Academy of Sciences, uncovers the unique dynamics governing ...

have shown how the recycling of ribosomes at the so-called endoplasmic reticulum (ER) functions. In the process, they discovered the role of an enzyme, a special E3 ligase that joins a small ...

Our research group studies the mechanisms of protein trafficking and quality control at the endoplasmic reticulum (ER) in mammalian cells. A major focus of research is on the COPII protein machinery ...

In biology textbooks, the endoplasmic reticulum is often portrayed as a distinct, compact organelle near the nucleus, and is ...

She studied the regulatory mechanisms of GPI-inositol deacylation of GPI-anchored proteins (GPI-APs) in endoplasmic reticulum (ER) in Morihisa Fujita and Xiaodong Gao's lab. She joined the Spencer lab ...

Transient Ca 2+ fluctuations on the surface of the endoplasmic reticulum (ER) can induce liquid-liquid phase separation (LLPS) of the autophagy initiation complex FIP200, forming FIP200 puncta and ...