This illustration depicts the process of enzyme catalysis. The enzyme (blue) binds to its substrate (red) to form an enzyme-substrate complex. The enzyme then catalyzes the conversion of the substrate ...

During proteolysis, the γ-secretase enzyme binds together in a complex initially with APP and then with subsequent intermediate forms of the protein as it is trimmed. To test the effects of FAD ...

Here, the authors use full-length Mpro protein as substrate and demonstrate that L50F can promote the formation of enzyme-substrate complex and thus contribute to nirmatrelvir resistance.

However, the complex structure of wood has been ... and researchers did not have a suitable feed, or "substrate," for the ...

This results in the particles colliding less often, which means there will be fewer successful collisions between the substrate and the enzyme’s active site. As the temperature increases ...

Here we explore peptide inhibitors of Cdc20, a substrate-recognition subunit and activator of the E3 ubiquitin ligase the anaphase promoting complex/cyclosome (APC/C) that is essential in mitosis and ...