facilitating a reaction by lowering the transition state energy by virtue of increased favorable interactions in the enzyme–transition state species and the process of stopping unwanted side ...

Entropic guidance was suggested based on spatial constraints of thermal fluctuations of NADH that result from the active site geometry (highly conserved in dehydrogenases) in a manner that enhances ...

A series of rodent experiments showed that even with abundant food and water, personal space is essential to prevent societal collapse, but Universe 25's relevance to humans remains disputed. Meet the ...

A transition-state mimic has the power to bind an enzyme at its tipping point as strongly as any available inhibitor and more strongly than most, preventing enzymatic activity. In order to replicate ...

Every year, thousands of tons of brown algae are extracted from the seabed to obtain compounds such as alginates, a polymer ...

Researchers have deciphered the mechanism by which a type of enzyme, called alginate lyase, is capable of degrading these ...

Scientists have known that, when the pancreas becomes inflamed, acinar cells, which produce digestive enzymes, begin to ...

Johns Hopkins Medicine scientists say they have found a pattern of so-called epigenetic “marks” in a transition state between normal and pancreatic cancer cells in mice, and that the normal cells may ...

Scientists say they have found a pattern of so-called epigenetic “marks” in a transition state between normal and pancreatic ...